Vitamin D and Prostate Cancer Risk
Prostate cancer is a progressive, multistep disease which presents many stages for intervention. Microscopic cancer is found in the prostate beginning by age 30 in about 20% of men, and…
Ecological Studies of the UVB–Vitamin D–Cancer Hypothesis
Background/Aim: This paper reviews ecological studies of the ultraviolet-B (UVB)–vitamin D–cancer hypothesis based on geographical variation of cancer incidence and/or mortality rates. Materials and Methods: The review is based largely…
Mechanisms of the Anti-Cancer and Anti-Inflammatory Actions of Vitamin D
Calcitriol, the hormonally active form of vitamin D, is being evaluated in clinical trials as an anti-cancer agent. Calcitriol exerts multiple anti-proliferative, pro-apoptotic, and pro-differentiating actions on various malignant cells…
Meta-analysis of vitamin D, calcium and the prevention of breast cancer
Vitamin D and calcium intake have been suggested to have protective effects against breast cancer; however, the data have been inconclusive. The present meta-analysis examined the overall effects of vitamin…