Lycopene and Cancer
Epidemiological and human clinical trials suggest that dietary intake of tomatoes or lycopene protects against cancers of the prostate, breast, cervix, ovary, endometrium, lung, bladder, oral cavity, esophagus, stomach, colon,…
Selective Inhibition of Cell Proliferation by Lycopene in MCF-7 Breast Cancer Cells In vitro: A Proteomic Analysis
Lycopene, a red pigmented carotenoid present in many fruits and vegetables such as tomatoes, has been associated with the reduced risk of breast cancer. This study sought to identify proteins…
The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention1,2,3,4
Evidence from epidemiologic studies has suggested that carotenoids, and lycopene in particular, decrease the risk of cancer: however, not all studies support this view. To gain insight into the molecular…
Broccoli-derived phytochemicals indole-3-carbinol and 3,3′-diindolylmethane exerts concentration-dependent pleiotropic effects on prostate cancer cells: Comparison with other cancer preventive phytochemicals
In the present studies, we utilized prostate cancer cell culture models to elucidate the mechanisms of action of broccoli-derived phytochemicals 3,3′-diindolylmethane (DIM) and indole-3-carbinol (I3C). We found DIM and I3C…