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Three patients were selected at random from a group of approximately 50 chronic hepatitis C patients. Each patient was maintained on a dose of 600 mg of alpha-lipoic acid per day in 2 divided doses of 300 mg, as well as silymarin at 900 mg/day in 3 divided doses of 300 mg and selenomethionine at 400 ug/day in 2 divided portions of 200 ug. The patients were also prescribed 2 vitamin B-100 capsules daily along with 1,000-6,000 mg/day of vitamin C, 400 IU/day of vitamin E and a mineral supplement. The patients were requested to eat a daily diet that included at least 6 servings of fresh vegetables and fruit, 4 ounces or less of meat per meal and 8 glasses of fresh water. Patients were encouraged to reduce their stress levels and take part in an exercise program that included at least a 1-mile walk, 3 times per week. These patients improved quickly following this program, and their laboratory values were markedly improved. Liver transplantation was avoided, and the patients went back to work, carrying out their normal activities and were feeling healthy. One year of the triple antioxidant therapy cost less than $2,000, as compared with more than $300,000 a year for liver transplant surgery. The author suggests that prior to liver transplant surgery or during the transplant evaluation process, conservative triple antioxidant treatment should be considered. Laboratory values tested that were reduced were SGPT levels, AFP levels, viral load and, in one case, blood sugar.