Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer-Norfolk prospective population study

Background: The relation between plasma vitamin C and risk of stroke remains unclear. Although clinical trials showed no significant benefit of vitamin C supplementation in reducing stroke risk, they were…

Continue ReadingPlasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer-Norfolk prospective population study

Antioxidant properties of alpha-lipoic acid: effects on red blood membrane permeability and adaptation of isolated rat heart to reversible ischemia

Abstract  The aim of our work was to study (1) the antioxidant properties of lipoic acid (LA) and its reduced metabolite dihydrolipoic acid (DHLA) formed by reduction of LA and…

Continue ReadingAntioxidant properties of alpha-lipoic acid: effects on red blood membrane permeability and adaptation of isolated rat heart to reversible ischemia

a-Lipoic Acid Prevents the Increase in Atherosclerosis Induced by Diabetes in Apolipoprotein E-Deficient Mice Fed High-Fat/Low-Cholesterol Diet

Considerable evidence indicates that hyperglycemia increases oxidative stress and contributes to the increased incidence of atherosclerosis and cardiovascular complications in diabetic patients. To examine the effect of α-lipoic acid, a…

Continue Readinga-Lipoic Acid Prevents the Increase in Atherosclerosis Induced by Diabetes in Apolipoprotein E-Deficient Mice Fed High-Fat/Low-Cholesterol Diet

Alpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice

Abstract Objective  To test the ability of alpha-lipoic acid (LA) to attenuate the development of collagen-induced arthritis (CIA) in mice. Methods  Mice were divided into three groups and treated with…

Continue ReadingAlpha-lipoic acid suppresses the development of collagen-induced arthritis and protects against bone destruction in mice