Purpose The purpose of this article is to review current evidence available for -lipoic acid (ALA) and its ability to improve symptoms of peripheral diabetic neuropathy (PDN). Methods This article…
Mitochondria produce reactive oxygen species that may contribute to vascular dysfunction. Alpha-lipoic acid and acetyl-L-carnitine reduce oxidative stress and improve mitochondrial function. In a double blind, crossover study, we examined…
Abstract Aims: To determine the efficacy and safety of 600 mg of a-lipoic acid given i.v. over 3 weeks in diabetic patients with symptomatic polyneuropathy. Methods: We searched the database…
The authors, in a previous article, described the long-term survival of a man with pancreatic cancer and metastases to the liver, treated with intravenous alpha-lipoic acid and oral low-dose naltrexone…