A Randomized, Controlled Trial of Doxycycline and Rifampin for Patients with Alzheimer’s Disease

Objectives: To assess whether doxycycline and rifampin have a therapeutic role in patients with Alzheimer's disease (AD). Design: Randomized, triple-blind, controlled trial. Setting: Three tertiary care and two community geriatric…

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The infection connection: Helicobacter pylori is more than just the cause of gastric ulcers—it offers an unprecedented opportunity to study changes in human microecology and the nature of chronic disease

When Barry Marshall drank a broth of Helicobacter pylori in the mid-1980s, he hoped to prove that the bacteria cause gastric ulcers, a common complaint worldwide. Sure enough, Marshall, then…

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Alzheimer’s Disease and Peripheral Infections: The Possible Contribution from Periodontal Infections, Model and Hypothesis

Alzheimer's disease (AD) affects approximately 4.5 million people in the U.S. and this number will increase as the population ages and the life-span increases. Therefore, of paramount importance is identifying…

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