Prospective study of serum selenium concentrations and esophageal and gastric cardia cancer, heart disease, stroke, and total death.

Background: We previously reported an inverse association between prediagnostic serum selenium concentrations and the risk of oesophageal squamous cell carcinoma (ESCC) and gastric cardia cancer (GCC) but not gastric noncardia…

Continue ReadingProspective study of serum selenium concentrations and esophageal and gastric cardia cancer, heart disease, stroke, and total death.

Selenium in Intensive Care (SIC): Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock *.

Objective: Sepsis is associated with an increase in reactive oxygen species and low endogenous antioxidative capacity. We postulated that high-dose supplementation of sodium-selenite would improve the outcome of patients with…

Continue ReadingSelenium in Intensive Care (SIC): Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock *.

An increase in selenium intake improves immune function and poliovirus handling in adults with marginal selenium status.

Background: Dietary selenium intakes in many countries, including the United Kingdom, are lower than international recommendations. No functional consequences of these lower intakes have been recognized, although experimental studies suggest…

Continue ReadingAn increase in selenium intake improves immune function and poliovirus handling in adults with marginal selenium status.