Background: We previously reported an inverse association between prediagnostic serum selenium concentrations and the risk of oesophageal squamous cell carcinoma (ESCC) and gastric cardia cancer (GCC) but not gastric noncardia…
Se is an unusual trace element in having its own codon in mRNA that specifies its insertion into selenoproteins as selenocysteine (SeCys), by means of a mechanism requiring a large…
Objective: Sepsis is associated with an increase in reactive oxygen species and low endogenous antioxidative capacity. We postulated that high-dose supplementation of sodium-selenite would improve the outcome of patients with…
Background: Dietary selenium intakes in many countries, including the United Kingdom, are lower than international recommendations. No functional consequences of these lower intakes have been recognized, although experimental studies suggest…