Vascular endothelial function and oxidative stress mechanisms in patients with Behçet’s syndrome

OBJECTIVES We sought to test the hypothesis that vascular endothelial function is impaired in Behçet’s syndrome and reflects increased levels of oxidative stress.   BACKGROUND Behçet’s syndrome is a multisystem…

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Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo.

A common feature of cigarette-smoke (CS)-associated diseases such as atherosclerosis and pulmonary emphysema is the activation, aggregation, and adhesion of leukocytes to micro- and macrovascular endothelium. A previous study, using…

Continue ReadingVitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo.

Vitamin C Improves Endothelial Dysfunction of Epicardial Coronary Arteries in Hypertensive Patients

Background There is evidence for increased formation of free radicals in patients with hypertension, raising the possibility that NO is inactivated by free radicals, which impairs coronary endothelial function. Therefore,…

Continue ReadingVitamin C Improves Endothelial Dysfunction of Epicardial Coronary Arteries in Hypertensive Patients