Cancer

Broccoli-derived phytochemicals indole-3-carbinol and 3,3′-diindolylmethane exerts concentration-dependent pleiotropic effects on prostate cancer cells: Comparison with other cancer preventive phytochemicals

In the present studies, we utilized prostate cancer cell culture models to elucidate the mechanisms of action of broccoli-derived phytochemicals 3,3′-diindolylmethane (DIM) and indole-3-carbinol (I3C). We found DIM and I3C…

Continue ReadingBroccoli-derived phytochemicals indole-3-carbinol and 3,3′-diindolylmethane exerts concentration-dependent pleiotropic effects on prostate cancer cells: Comparison with other cancer preventive phytochemicals

The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention1,2,3,4

Evidence from epidemiologic studies has suggested that carotenoids, and lycopene in particular, decrease the risk of cancer: however, not all studies support this view. To gain insight into the molecular…

Continue ReadingThe role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention1,2,3,4

Selective Inhibition of Cell Proliferation by Lycopene in MCF-7 Breast Cancer Cells In vitro: A Proteomic Analysis

Lycopene, a red pigmented carotenoid present in many fruits and vegetables such as tomatoes, has been associated with the reduced risk of breast cancer. This study sought to identify proteins…

Continue ReadingSelective Inhibition of Cell Proliferation by Lycopene in MCF-7 Breast Cancer Cells In vitro: A Proteomic Analysis