Intake of folate, vitamins B6, B12 and methionine and risk of pancreatic cancer in a large population-based case–control study

Objective Folate and other methyl-group nutrients may play a key role in pancreatic carcinogenesis through their effects on DNA integrity. We examined the association between pancreatic cancer and intake of…

Continue ReadingIntake of folate, vitamins B6, B12 and methionine and risk of pancreatic cancer in a large population-based case–control study

Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway

Background and Aims:  Available medical therapies against pancreatic cancer are largely ineffective and have many side-effects. Physiologically, vitamins K1 and K2 (VK) act as co-factors for γ-carboxylation of prothrombin and…

Continue ReadingNaturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway

Total and Cancer Mortality After Supplementation With Vitamins and Minerals: Follow-up of the Linxian General Population Nutrition Intervention Trial

Background The General Population Nutrition Intervention Trial was a randomized primary esophageal and gastric cancer prevention trial conducted from 1985 to 1991, in which 29 584 adult participants in Linxian, China,…

Continue ReadingTotal and Cancer Mortality After Supplementation With Vitamins and Minerals: Follow-up of the Linxian General Population Nutrition Intervention Trial