Hyperhomocysteinemia and vitamin B6 deficiency: New risk markers for nonvalvular atrial fibrillation?*

Background A recent “ex-vivo” study showed that nonvalvular atrial fibrillation (NVAF) is associated with enhanced activity of metalloproteinases at the atrial level, and in animal models homocysteine (Hcy) is able…

Continue ReadingHyperhomocysteinemia and vitamin B6 deficiency: New risk markers for nonvalvular atrial fibrillation?*

Sun Exposure, Vitamin D Receptor Gene Polymorphisms, and Risk of Advanced Prostate Cancer

Substantial experimental evidence indicates that the hormonal form of vitamin D promotes the differentiation and inhibits the proliferation, invasiveness, and metastasis of human prostatic cancer cells. Results from epidemiologic studies…

Continue ReadingSun Exposure, Vitamin D Receptor Gene Polymorphisms, and Risk of Advanced Prostate Cancer