Aims/hypothesis Hyperglycaemia-induced mitochondrial overproduction of reactive oxygen species (ROS) is central to the pathogenesis of endothelial damage in diabetes. R-(+)-α-lipoic acid has advantages over classic antioxidants, as it distributes to…
Oxidative stress is increased in the retina in diabetes, and it is considered to play an important role in the development of retinopathy. α-Lipoic acid, a thiol antioxidant, has been…
Chromium (Cr) picolinate (CrPic) is a widely used nutritional supplement for optimal insulin function. A relationship among Cr status, diabetes, and associated pathologies has been established. Virtually all trials using…
Background: Many patients present to emergency departments with chest pain but little is known about this population and the safest, most efficient testing strategies. Aims: We assessed clinical risk stratification…