Curcumin and cancer: An “old-age” disease with an “age-old” solution
Cancer is primarily a disease of old age, and that life style plays a major role in the development of most cancers is now well recognized. While plant-based formulations have…
Curcumin for chemoprevention of colon cancer
The most practical approach to reduce the morbidity and mortality of cancer is to delay the process of carcinogenesis through the use of chemopreventive agents. This necessitates that safer compounds,…
Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells
Background: A major challenge in cancer chemotherapy has been developing safe and clinically efficacious chemotherapeutic agents. With its low toxicity profile, curcumin (diferuloylmethane), a naturally occurring flavinoid derived from the…
Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-κB and nuclear factor-κB – regulated gene products in IFN-α – sensitive and IFN-α – resistant human bladder cancer cells
Bladder cancer mortality varies between the countries; whereas being highest in Western countries, it is lowest in Eastern countries, such as India. Cigarette smoking is one of the major risk…
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