Bone marrow-derived mesenchymal stem cell attenuates skin fibrosis development in mice

Recent studies showed that mesenchymal stem cell (MSC) transplantation significantly alleviated tissue fibrosis; however, little is known about the efficacy on attenuating cutaneous scar formation. In this study, we established…

Continue ReadingBone marrow-derived mesenchymal stem cell attenuates skin fibrosis development in mice

Bone marrow-derived stem cells ameliorate hepatic fibrosis by down-regulating interleukin-17

Background Accumulating evidences have identified the immunoregulatory features of stem cells. In this study, the immunoregulation of bone marrow-derived stem cells (BMSCs) transplanted into patients with HBV-related decompensated cirrhosis and…

Continue ReadingBone marrow-derived stem cells ameliorate hepatic fibrosis by down-regulating interleukin-17

A clinical trial report of autologous bone marrow‑derived mesenchymal stem cell transplantation in patients with spinal cord injury

Spinal cord injury (SCI) is a severe neurological disease. An effective strategy for the treatment of SCI is urgently required. Stem cell transplantation has emerged as a viable therapeutic option…

Continue ReadingA clinical trial report of autologous bone marrow‑derived mesenchymal stem cell transplantation in patients with spinal cord injury