Therapeutic role of coenzyme Q10 in Parkinson’s disease
Mitochondrial dysfunction has been well established to occur in Parkinson's disease (PD) and appears to play a role in the pathogenesis of the disorder. A key component of the mitochondrial…
Mitochondrial dysfunction and molecular pathways of disease
Since the first mitochondrial dysfunction was described in the 1960s, the medicine has advanced in its understanding the role mitochondria play in health, disease, and aging. A wide range of…
Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death-associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson’s disease: protection by -lipoic acid
Parkinson’s disease (PD), a neurodegenerative disorder, causes severe motor impairment due to loss of dopaminergic neurons in substantia nigra pars compacta (SNpc). MPTP, a neurotoxin that causes dopaminergic cell loss…
Cadmium inhibits the electron transfer chain and induces Reactive Oxygen Species
Recent research indicates that cadmium (Cd) induces oxidative damage in cells; however, the mechanism of the oxidative stress induced by this metal is unclear. We investigated the effects of…
- Go to the previous page
- 1
- …
- 451
- 452
- 453
- 454
- 455
- 456
- 457
- …
- 537
- Go to the next page