Metals differ from most synthetic organic chemicals in that their clinical manifestations are well known and methods for their measurement in the body are generally well established. Since metals are…
Cisplatin [cis-diamminechloroplatinum(II)] has proved itself as a potent antineoplastic agent. However, nephrotoxicity, neurotoxicity, gastrointestinal toxicity, myelosuppression, and ototoxicity interfere with its therapeutical efficacy. Forced diuresis reduces nephrotoxicity, effectively leaving neurotoxicity…
Hearing deficits are a frequent consequence of both developmental and adult methyl mercury exposure in humans. However, a detailed characterization of these deficits has not been performed in either humans…
Purpose: Chronic diseases can develop through metabolic disturbances in trace elements and vitamins, and be maintained by environmental toxins. In order to gain more insight into these complex interactions and…