Glutathione and Glutamate Levels in the Diaphragm of Patients with Chronic Obstructive Pulmonary Disease

Recently, decreased glutamate (Glu) and reduced glutathione (GSH) levels were reported in the quadriceps femoris of patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was…

Continue ReadingGlutathione and Glutamate Levels in the Diaphragm of Patients with Chronic Obstructive Pulmonary Disease

Depletion of Glutathione S-transferase P1 Induces Apoptosis in Human Lung Fibroblasts

Glutathione S-transferase P1 (GSTP1) is one of the xenobiotic-metabolizing and antioxidant enzymes, identified in the peripheral lungs. Recently, the authors reported the association between GSTP1 gene polymorphism and susceptibility to…

Continue ReadingDepletion of Glutathione S-transferase P1 Induces Apoptosis in Human Lung Fibroblasts

Competition for Glutathione Precursors Between the Immune System and the Skeletal Muscle: Pathogenesis of Chronic Fatigue Syndrome

The chronic fatigue syndrome (CFS) is typically associated or follows a recognized or presumed infection. Abnormalities of both humoral and cellular immunity have been demonstrated in a substantial proportion of…

Continue ReadingCompetition for Glutathione Precursors Between the Immune System and the Skeletal Muscle: Pathogenesis of Chronic Fatigue Syndrome