Depletion of plasma vitamin C but not of vitamin E in response to cardiac operations

The whole-body inflammatory response produced by cardiopulmonary bypass is an important cause of perioperative morbidity after cardiac operations. This inflammatory response produces reactive oxygen species and other cytotoxic substances, such…

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Vitamin C attenuates abnormal vasomotor reactivity in spasm coronary arteries in patients with coronary spastic angina

Objectives. This study sought to examine effect of vitamin C, an antioxidant, on the abnormal vasomotor reactivity in spasm coronary arteries.   Background. Oxygen free radicals generated in the arterial…

Continue ReadingVitamin C attenuates abnormal vasomotor reactivity in spasm coronary arteries in patients with coronary spastic angina

Vascular endothelial function and oxidative stress mechanisms in patients with Behçet’s syndrome

OBJECTIVES We sought to test the hypothesis that vascular endothelial function is impaired in Behçet’s syndrome and reflects increased levels of oxidative stress.   BACKGROUND Behçet’s syndrome is a multisystem…

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Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo.

A common feature of cigarette-smoke (CS)-associated diseases such as atherosclerosis and pulmonary emphysema is the activation, aggregation, and adhesion of leukocytes to micro- and macrovascular endothelium. A previous study, using…

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