Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson’s disease.

A population-based case-control study was conducted in the Henry Ford Health System (HFHS) in metropolitan Detroit to assess occupational exposures to manganese, copper, lead, iron, mercury and zinc as risk…

Continue ReadingOccupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson’s disease.

Catecholamine toxicity: a proposal for the molecular pathogenesis of manganese neurotoxicity and Parkinson’s disease.

An hypothesis is presented which attempts to relate the pathogenesis of both manganese neurotoxicity and Parkinson's disease to cytotoxicity from products of catecholamine oxidation. These include the products resulting from…

Continue ReadingCatecholamine toxicity: a proposal for the molecular pathogenesis of manganese neurotoxicity and Parkinson’s disease.

The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure

Methods and results Thirty CHF patients [age 75.4 (0.7), mean (SEM), LV ejection fraction (LVEF) 35%] were randomized to receive capsules containing a combination of high-dose micronutrients (calcium, magnesium, zinc,…

Continue ReadingThe effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure