Lipoic acid (LA) is a small molecule with only two kinds of functional groups. It is a naturally-occurring co-factor present in many multi-enzyme complexes regulating metabolism. It is present in…
Abstract Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in…
The authors describe the long-term survival of a patient with pancreatic cancer without any toxic adverse effects. The treatment regimen includes the intravenous alpha-lipoic acid and low-dose naltrexone (ALA-N) protocol…
Alpha-lipoic acid (LA), the metabolic antioxidant, was evaluated for its potential to protect against Cr6+-induced DNA damage. Potassium dichromate was administered to Swiss albino mice orally ad libitum at the…