Effect of lycopene on cell viability and cell cycle progression in human cancer cell lines

Background: Lycopene, a major carotenoid component of tomato, has a potential anticancer activity in many types of cancer. Epidemiological and clinical trials rarely provide evidence for mechanisms of the compound’s…

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Selective Inhibition of Cell Proliferation by Lycopene in MCF-7 Breast Cancer Cells In vitro: A Proteomic Analysis

Lycopene, a red pigmented carotenoid present in many fruits and vegetables such as tomatoes, has been associated with the reduced risk of breast cancer. This study sought to identify proteins…

Continue ReadingSelective Inhibition of Cell Proliferation by Lycopene in MCF-7 Breast Cancer Cells In vitro: A Proteomic Analysis

The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention1,2,3,4

Evidence from epidemiologic studies has suggested that carotenoids, and lycopene in particular, decrease the risk of cancer: however, not all studies support this view. To gain insight into the molecular…

Continue ReadingThe role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention1,2,3,4