Alpha-lipoic acid (ALA) and vitamin E (VE) are normally present in human diet and their side-effects derived from oral supplementation are very rare. Interestingly, a combination of these antioxidants has…
Purpose Alpha-lipoic acid is an essential cofactor for mitochondrial respiratory enzymes that improves mitochondrial function. We previously reported that alpha-lipoic acid markedly reduced body weight gain in rodents. The purpose…
AIM: To estimate the late duration of the effect of 3-week intravenous alpha-lipoic acid (alpha-LA) administration. SUBJECTS AND METHODS: The study included patients with symptoms of myodiabetic polyneuropathy. The authors…
Fibromyalgia (FM) is a chronic pain syndrome with unknown etiology. Recent studies have shown evidence demonstrating that mitochondrial dysfunction and oxidative stress may have a role in the pathophysiology of…