Type 2 Diabetes Mellitus (T2DM) which is characterised by insulin resistance, is closely linked to the triad of glucolipotoxicity, inflammation and oxidative stress. Increased adiposity, leading to increased free fatty…
Alpha-lipoic acid (ALA) and vitamin E (VE) are normally present in human diet and their side-effects derived from oral supplementation are very rare. Interestingly, a combination of these antioxidants has…
Purpose Alpha-lipoic acid is an essential cofactor for mitochondrial respiratory enzymes that improves mitochondrial function. We previously reported that alpha-lipoic acid markedly reduced body weight gain in rodents. The purpose…