Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells

Background: A major challenge in cancer chemotherapy has been developing safe and clinically efficacious chemotherapeutic agents. With its low toxicity profile, curcumin (diferuloylmethane), a naturally occurring flavinoid derived from the…

Continue ReadingCurcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells

Cimetidine inhibits in vivo growth of human colon cancer and reverses histamine stimulated in vitro and in vivo growth.

The effect of histamine and cimetidine on the growth of four human colon cancer cell lines was studied. Histamine significantly stimulated the uptake of tritiated thymidine in vitro in a…

Continue ReadingCimetidine inhibits in vivo growth of human colon cancer and reverses histamine stimulated in vitro and in vivo growth.