-Lipoic acid (LA), a naturally occurring dithiol compound, has long been known as an essential cofactor for mitochondrial bioenergetic enzymes. Aside from its enzymatic role, in vitro and in vivo…
Background and Aims: The progression of diabetes mellitus is concomitant with decrease of the regenerative capacity of skeletal muscle and treatment with insulin can prevent futher atrophy of slow and…
Background: Mood disorders are associated with decrements in cognitive function, which are insufficiently treated with contemporary pharmacotherapies. Objectives: To evaluate the putative neurotherapeutic effects of the mitochondrial cofactors, L-carnitine, acetyl-L-carnitine,…
Lipoic acid (ALA) has been identified as a powerful antioxidant found naturally in our diets, but appears to have increased functional capacity when given as a supplement in the form…