Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson’s disease.

A population-based case-control study was conducted in the Henry Ford Health System (HFHS) in metropolitan Detroit to assess occupational exposures to manganese, copper, lead, iron, mercury and zinc as risk…

Continue ReadingOccupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson’s disease.

Catecholamine toxicity: a proposal for the molecular pathogenesis of manganese neurotoxicity and Parkinson’s disease.

An hypothesis is presented which attempts to relate the pathogenesis of both manganese neurotoxicity and Parkinson's disease to cytotoxicity from products of catecholamine oxidation. These include the products resulting from…

Continue ReadingCatecholamine toxicity: a proposal for the molecular pathogenesis of manganese neurotoxicity and Parkinson’s disease.