Yearly Archives: 2008

Comparative study of natural antioxidants – curcumin, resveratrol and melatonin – in cadmium-induced oxidative damage in mice

The present study was designed to examine the antioxidative effect of curcumin, resveratrol and melatonin pre-treatment on cadmium-induced oxidative damage and cadmium distribution in an experimental model in mice. Male…

Continue ReadingComparative study of natural antioxidants – curcumin, resveratrol and melatonin – in cadmium-induced oxidative damage in mice

Melatonin inhibits both ER? activation and breast cancer cell proliferation induced by a metalloestrogen, cadmium

Cadmium (Cd) is a heavy metal affecting human health both through environmental and occupational exposure. There is evidence that Cd accumulates in several organs and is carcinogenic to humans. In…

Continue ReadingMelatonin inhibits both ER? activation and breast cancer cell proliferation induced by a metalloestrogen, cadmium

Melatonin as an antibiotic: new insights into the actions of this ubiquitous molecule.

The incidence of serious infections caused by multidrug-resistant gram-positive and gram-negative bacteria has been increasing rapidly worldwide despite advances in antibacterial therapy in the last two decades. Among multidrug-resistant gram-positive…

Continue ReadingMelatonin as an antibiotic: new insights into the actions of this ubiquitous molecule.

Melatonin modulates the cadmium-induced expression of MT-2 and MT-1 metallothioneins in three lines of human tumor cells (MCF-7, MDA-MB-231 and HeLa)

Cadmium (Cd) is a human carcinogen present in tobacco smoke and contaminated industrial soils. Metallothioneins (MTs) are intracellular proteins involved in protecting against Cd. The toxic effects of Cd can…

Continue ReadingMelatonin modulates the cadmium-induced expression of MT-2 and MT-1 metallothioneins in three lines of human tumor cells (MCF-7, MDA-MB-231 and HeLa)