Systemic Increase of Oxidative Nucleic Acid Damage in Parkinson’s Disease and Multiple System Atrophy

8-hydroxy-2′-deoxyguanosine (8-OHdG) or 8-hydroxyguanosine (8-OHG), a product of oxidized DNA or RNA, is a good marker of oxidative cellular damage. In this study, we measured the 8-OHdG/8-OHG levels in the…

Continue ReadingSystemic Increase of Oxidative Nucleic Acid Damage in Parkinson’s Disease and Multiple System Atrophy

The association between blood metal concentrations and heart rate variability: a cross-sectional study

 Objectives: Analysis of heart rate variability (HRV) is useful for measuring cardiovascular autonomic function. The effects of blood metals on cardiovascular autonomic function have not been studied extensively. The objective…

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Amyotrophic Lateral Sclerosis and Exposure to Environmental Toxins: An Australian Case-Control Study

It has been suggested that environmental toxins could be risk factors for sporadic amyotrophic lateral sclerosis (SALS). We therefore analysed epidemiological data on 179 SALS cases and 179 age-, ethnicity-…

Continue ReadingAmyotrophic Lateral Sclerosis and Exposure to Environmental Toxins: An Australian Case-Control Study