Randomized controlled trial of high-dose sublingual immunotherapy to treat seasonal allergic rhinitis

Background Seasonal allergic rhinitis is common and troublesome. Sublingual immunotherapy (SLIT) has been proposed as an alternative to injection immunotherapy and might offer some advantages if it were effective and…

Continue ReadingRandomized controlled trial of high-dose sublingual immunotherapy to treat seasonal allergic rhinitis

A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract

Fifty-eight patients with well-documented history of seasonal rhinoconjunctivitis caused by grass pollens were allocated randomly on a double-blind basis to receive either sublingual therapy with a solution of purified, standardized…

Continue ReadingA double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract

Long-lasting effect of sublingual immunotherapy in children with asthma due to house dust mite: a 10-year prospective study

  Background Subcutaneous immunotherapy for respiratory allergy has shown a long-lasting efficacy after its discontinuation, whereas this evidence is still lacking for sublingual immunotherapy, despite the fact that it is…

Continue ReadingLong-lasting effect of sublingual immunotherapy in children with asthma due to house dust mite: a 10-year prospective study