Selenium and host defence towards viruses
The association between viral disease and nutrition has long been thought to be due to effects on the host immune system. This theory suggests that when a host is malnourished,…
Prospective study of serum selenium concentrations and esophageal and gastric cardia cancer, heart disease, stroke, and total death.
Background: We previously reported an inverse association between prediagnostic serum selenium concentrations and the risk of oesophageal squamous cell carcinoma (ESCC) and gastric cardia cancer (GCC) but not gastric noncardia…
Selenium in cancer prevention: a review of the evidence and mechanism of action
Se is an unusual trace element in having its own codon in mRNA that specifies its insertion into selenoproteins as selenocysteine (SeCys), by means of a mechanism requiring a large…
Selenium in Intensive Care (SIC): Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock *.
Objective: Sepsis is associated with an increase in reactive oxygen species and low endogenous antioxidative capacity. We postulated that high-dose supplementation of sodium-selenite would improve the outcome of patients with…