Lipoic Acid and Cardiovascular Disease1
Lipoic acid (ALA) has been identified as a powerful antioxidant found naturally in our diets, but appears to have increased functional capacity when given as a supplement in the form…
Effects of Alpha-Lipoic Acid Supplementation in Peripheral Arterial Disease: A Pilot Study
Objective: To examine whether 3 months of lipoic acid (LA) supplementation improved walking tolerance and delayed claudication pain onset in peripheral arterial disease (PAD). Design: Randomized, double-blind, controlled study. Setting:…
Lipoic Acid Prevents the Increase in Atherosclerosis Induced by Diabetes in Apolipoprotein E–Deficient Mice Fed High-Fat/Low-Cholesterol Diet
Considerable evidence indicates that hyperglycemia increases oxidative stress and contributes to the increased incidence of atherosclerosis and cardiovascular complications in diabetic patients. To examine the effect of -lipoic acid, a…
Oral Treatment With -Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy
OBJECTIVE—The aim of this trial was to evaluate the effects of -lipoic acid (ALA) on positive sensory symptoms and neuropathic deficits in diabetic patients with distal symmetric polyneuropathy (DSP). RESEARCH…