Glutathione: antioxidant and cell function regulator
The oxidation–reduction (redox) state of the pool of cellular thiols plays a central role in antioxidant defence and in the regulation of a large number of signal transduction pathways and…
Age-Associated Decline in Effective Immune Synapse Formation of CD4+ T Cells Is Reversed by Vitamin E Supplementation
Aging is associated with reduced IL-2 production and T cell proliferation. Vitamin E supplementation, in aged animals and humans, increases cell division and IL-2 production by naive T cells. The…
Melatonin, immune function and aging
Aging is associated with a decline in immune function (immunosenescence), a situation known to correlate with increased incidence of cancer, infectious and degenerative diseases. Innate, cellular and humoral immunity all…
Nutritional modulation of immune function
The inflammatory response to injury and infection, although an essential part of immune function, carries the risk of severe tissue depletion and immunosuppression. These outcomes increase morbidity and delay recovery.…
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