Brain Aluminum Distribution in Alzheimer’s Disease and Experimental Neurofibrillary Degeneration

Neurofibrillary degeneration is an important pathological finding in senile and presenile dementia of the Alzheimer type. Experimentally, aluminum induces neurofibrillary degeneration in neurons of higher mammals.  Aluminum concentrations approaching those…

Continue ReadingBrain Aluminum Distribution in Alzheimer’s Disease and Experimental Neurofibrillary Degeneration

Alzheimer’s disease: X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons

The elemental content of neurons of the hippocampus was studied by a combination of scanning electron microscopy and x-ray spectrometry in autopsy-derived brain tissue from three cases of senile dementia…

Continue ReadingAlzheimer’s disease: X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons