Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: Evidence from transgenic sensor mice

Endoplasmic reticulum (ER) stress-responsive alkaline phosphatase (ES-TRAP) serves as a sensitive indicator for ER stress. In response to heavy metals including cadmium, nickel and cobalt, hepatocytes and renal tubular cells…

Continue ReadingRapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: Evidence from transgenic sensor mice

Fine Particulate Air Pollution and Hospital Admission for Cardiovascular and Respiratory Diseases

Context  Evidence on the health risks associated with short-term exposure to fine particles (particulate matter ≤2.5 µm in aerodynamic diameter [PM2.5]) is limited. Results from the new national monitoring network…

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Long-term Air Pollution Exposure and Acceleration of Atherosclerosis and Vascular Inflammation in an Animal Model

Context  Recent studies have suggested a link between inhaled particulate matter exposure in urban areas and susceptibility to cardiovascular events; however, the precise mechanisms remain to be determined. Objective  To…

Continue ReadingLong-term Air Pollution Exposure and Acceleration of Atherosclerosis and Vascular Inflammation in an Animal Model