A clinical trial report of autologous bone marrow‑derived mesenchymal stem cell transplantation in patients with spinal cord injury

Spinal cord injury (SCI) is a severe neurological disease. An effective strategy for the treatment of SCI is urgently required. Stem cell transplantation has emerged as a viable therapeutic option…

Continue ReadingA clinical trial report of autologous bone marrow‑derived mesenchymal stem cell transplantation in patients with spinal cord injury

Bone marrow-derived stem cells ameliorate hepatic fibrosis by down-regulating interleukin-17

Background Accumulating evidences have identified the immunoregulatory features of stem cells. In this study, the immunoregulation of bone marrow-derived stem cells (BMSCs) transplanted into patients with HBV-related decompensated cirrhosis and…

Continue ReadingBone marrow-derived stem cells ameliorate hepatic fibrosis by down-regulating interleukin-17

Bone marrow-derived mesenchymal stem cell attenuates skin fibrosis development in mice

Recent studies showed that mesenchymal stem cell (MSC) transplantation significantly alleviated tissue fibrosis; however, little is known about the efficacy on attenuating cutaneous scar formation. In this study, we established…

Continue ReadingBone marrow-derived mesenchymal stem cell attenuates skin fibrosis development in mice

Restoration of Intracortical and Thalamocortical Circuits After Transplantation of Bone Marrow Mesenchymal Stem Cells Into the Ischemic Brain of Mice

Transplantation of bone marrow mesenchymal stem cells (BMSCs) provides a promising regenerative medicine for stroke. Whether BMSC therapy could repair ischemia-damaged neuronal circuits and recover electrophysiological activity has largely been…

Continue ReadingRestoration of Intracortical and Thalamocortical Circuits After Transplantation of Bone Marrow Mesenchymal Stem Cells Into the Ischemic Brain of Mice