The safety of autologous and metabolically fit bone marrow mesenchymal stromal cells in medically refractory Crohn’s disease – a phase 1 trial with three doses

Background Mesenchymal stromal cells ability to reset immune functionalities may be useful in Crohn's disease. Aim To perform a first-in-human phase 1 safety clinical trial of metabolically fit autologous bone…

Continue ReadingThe safety of autologous and metabolically fit bone marrow mesenchymal stromal cells in medically refractory Crohn’s disease – a phase 1 trial with three doses

Mesenchymal Stem Cell Therapy for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.

Recent advances in inflammatory bowel disease (IBD) therapeutics include novel medical, surgical, and endoscopic treatments. Among these, stem cell therapy is still in its infancy, though multiple studies suggest the…

Continue ReadingMesenchymal Stem Cell Therapy for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis.

Role of Autologous Bone Marrow Stem Cell Transplantation in the Treatment of Active Ulcerative Colitis

Background: Stem cell therapy was suggested to improve the quality of life to patients of UC through its powerful immunomodulatory effects and its ability to stimulate regeneration of intestinal mucosa.…

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Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated with herpes zoster: a case report

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with continuous or recurrent symptoms. A 42-year-old male patient with intermittent diarrhea accompanied by bloody mucopurulent stools was admitted to our…

Continue ReadingAutologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated with herpes zoster: a case report