Prostate cancer is one of the common cancers seen in males. Earlier studies that have used intravenous (IV) or oral vitamin C have shown an improvement in symptoms of cancer patients and have prolonged life in terminally ill cancer patients. Today, evidence suggests that high doses of intravenous vitamin C ranging from 50 to 100 g can increase the plasma concentration of vitamin C to 14000 μmol/L. When the concentration of vitamin C in the plasma is about 1000 μmol/L, vitamin C is selectively toxic to cancer cells. We report here a case study of a patient who has diagnosed prostate cancer of Gleason’s pattern 7. We found that, at the end of ten months of treatment with high dose IV vitamin C, the vascular tumor that was present before on the left mid-gland area of the prostate was no longer detectable on the ultrasound. In the light of the recent evidence showing anti-tumor activity of vitamin C, the role of high dose IV vitamin C for cancer should be considered further.