Dietary constituents of broccoli and other cruciferous vegetables: Implications for prevention and therapy of cancer

Over the past several decades, research on the action of bioactive constituents of plants has focused predominantly on their cancer-preventive properties. Today it can be explained why the consumption of…

Continue ReadingDietary constituents of broccoli and other cruciferous vegetables: Implications for prevention and therapy of cancer

Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells

Purpose: The existence of cancer stem cells (CSCs) in breast cancer has profound implications for cancer prevention. In this study, we evaluated sulforaphane, a natural compound derived from broccoli/broccoli sprouts,…

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Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines

Several evidences suggest that cancer cells have abnormal cholesterol biosynthetic pathways and prenylation of small guanosine triphosphatase proteins. Tomato lycopene has been suggested to have beneficial effects against certain types…

Continue ReadingLycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines

Lycopene Enhances Effect in Castration-Resistant Prostate Cancer Associated with Insulin-like Growth Factor I Receptor Levels1

is currently the most effective drug for the treatment of castration-resistant prostate cancer (CRPC), but it only extends life by an average of 2 months. Lycopene, an antioxidant phytochemical, has…

Continue ReadingLycopene Enhances Effect in Castration-Resistant Prostate Cancer Associated with Insulin-like Growth Factor I Receptor Levels1