Objective: To review the data that support the clinical use of melatonin in the treatment of burn patients, with special emphasis on the stimulation of the oxidative defense system, the…
Chronic sarcoidosis (CS) is often unresponsive to usual treatments. Melatonin, an immunoregulatory drug, was employed in CS patients in whom usual treatments were ineffective or induced severe side effects. Melatonin…
Mitochondrial defects have been linked to such devastating neurodegenerative diseases as Parkinson's, Huntington's, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS) and Alzheimer's as well as senile dementia's. Mitochondrial metabolic defects…
Mercury, cadmium, and other heavy metals have a high affinity for sulfhydryl (-SH) groups, inactivating numerous enzymatic reactions, amino acids, and sulfur-containing antioxidants (NAC, ALA, GSH), with subsequent decreased oxidant…